I. HyPercycle theory-Generalized Cycles-BMKI
A cycle or a generalized cycle in the mechanics was described as “Circular dynamic zero-dimensional space” (or CDZDS), by the author in his book <The Theory of Biomedical Knowledge Integration> [1]. Because, in contrast to a point or a 0-D object in the Euclidean space, a cycle in the real world is, similarly, featured by the finite dimensional measurement, rather than an infinite one in the theoretical world. Additionally, the most importance is that a real cycle has contents inside, which are moving constantly, in the most economical way where the result would be the origin, at last.
The concept of the generalized Cycles or GCs in the mechanics of the molecular biomedicines is inspired by the hypercycle theory proposed by Manfred Eigen and Peter Schuster [2,3], would be expected to cover the topics about the cycles (or circles or loops, such as the feedback loops), fluctuations or waves, oscillations or vibrations, … in the molecular biomedicines.
What is the fantastic experience for making a navigation or exploration in this kingdom. This is one reason why the topic is made as a part of the explorations of the “Biomedical Knowledge Integration” (or BMKI). The picture shown here is just a first step for the mysterious negative feedback loop about the hypothalamus-pituitary-thyroid (HPT) axis, which would affect nearly all cells in human body.
- Bao Hanfei: <The Theory of Biomedical Knowledge Integration> (Book, In Chinese), ZheJiang University Press, 2010
- Eigen and P. Schuster. The Hypercycle. A Principle of Natural Self-Organization. Berlin: Springer–Verlag, 1979.
- Josep Sardanyes: THE HYPERCYCLE: FROM MOLECULAR TO ECOSYSTEMS DYNAMICS, https://www.researchgate.net/publication/230887666_The_Hypercycle_from_molecular_to_ecosystems_dynamics
(Updated on 2024-02-01)
